Disrupt Non-Thermal-Based Revolutionary Ways for Postharvest Food Security: Mechanisms, Hurdles, and Future Prospects with Focus on Containment of Mycotoxins and Fungal Screenings
Keywords:
Postharvest food safety, Fungal contamination, Mycotoxins, Non-thermal technologies, Food preservation, Sustainable processingAbstract
Global food security, public health, and agricultural sustainability face severe dangers from fungal contamination and mycotoxin accumulation which occur during postharvest processing of food. Traditional thermal processing methods fail to remove resistant fungal spores from food products, resulting in loss of nutritional and sensory quality. The development of new non-thermal technologies that provide sustainable solutions for fungal control and mycotoxin detoxification has become increasingly popular as an environmentally friendly approach. This analysis investigates the fundamental scientific principles and operational mechanisms and current technical progress of essential non-thermal technologies, which include high hydrostatic pressure, ozone treatment, ultraviolet radiation and pulsed electric fields and cold plasma and nanotechnology-based methods. The discussion explores how these technologies serve as antifungal solutions that protect against mycotoxins while remaining usable across different types of food products. The review presents primary study impediments, which include problems with industrial scalability, expensive operational expenses and existing regulatory restrictions. Integrated systems which combine artificial intelligence with smart monitoring tools will create efficient safe operations according to future system development. Non-thermal technologies provide environmentally friendly solutions which improve food safety during postharvest processing while maintaining food quality in contemporary food distribution systems.
References
Abou Dib, A., Assaf, J. C., El Khoury, A., El Khatib, S., Koubaa, M., & Louka, N. (2022). Single, subsequent, or simultaneous treatments to mitigate mycotoxins in solid foods and feeds: A critical review. Foods, 11(20), Article e3304. https://doi.org/10.3390/foods11203304
Adepoju, M., Verheecke-Vaessen, C., Pillai, L. R., Phillips, H., & Cervini, C. (2024). Unlocking the potential of teff for sustainable, gluten-free diets and addressing production challenges: A review. Foods, 13(21), Article e3394. https://doi.org/10.3390/foods13213394
Arumugam, D., Li, S., Rao, M., Peng, R., Liu, H., Huo, B., & Wang, J. (2025). Non-thermal technologies for seafood preservation and shelf-life extension: A detailed review. Food Quality and Safety, Article fyaf046. https://doi.org/10.1093/fqsafe/fyaf046
Atnafu, B., Garbaba, C. A., Lemessa, F., Migheli, Q., Sulyok, M., & Chala, A. (2024). Multiple mycotoxins in maize grains from Ethiopia. Mycotoxin Research, 40(3), 389–399. https://doi.org/10.1007/s12550-024-00536-3
Casu, A., Camardo Leggieri, M., Toscano, P., & Battilani, P. (2024). Climate change and mycotoxin contamination: A comprehensive review. Comprehensive Reviews in Food Science and Food Safety, 23(2), Article e13323. https://doi.org/10.1111/1541-4337.13323
Delgado-Ospina, J., & Rinaldi, M. (2025). Enhancing postharvest food safety: Role of non-thermal technologies in fungal control. In C. Chaves, C. D. Grande-Tovar, & G. Cordero-Bueso (Eds.), Application of novel technologies for the inactivation and reduction of fungi and mycotoxins (p. 73–99). Frontiers.
Doshi, P., & Šerá, B. (2023). Role of non-thermal plasma in Fusarium inactivation and mycotoxin decontamination. Plants, 12(3), Article e627. https://doi.org/10.3390/plants12030627
Drishya, C., Yoha, K. S., Perumal, A. B., Moses, J. A., Anandharamakrishnan, C., & Balasubramaniam, V. M. (2022). Impact of nonthermal food processing techniques on mycotoxins and fungi. International Journal of Food Science and Technology, 57(4), 2140–2148. https://doi.org/10.1111/ijfs.15444
Ekwomadu, T., Mwanza, M., & Musekiwa, A. (2022). Mycotoxin-linked mutations and cancer risk. International Journal of Environmental Research and Public Health, 19(13), Article e7754. https://doi.org/10.3390/ijerph19137754
El-Sayed, M. T., Mohamed, H. H., & Ismaiel, A. A. (2022). Detoxification of ochratoxin A using ultraviolet irradiation. NeuroQuantology, 20(15), 5862–5875.
Emadi, A., Eslami, M., Yousefi, B., & Abdolshahi, A. (2022). Reduction of aflatoxin B1 by probiotic bacteria: A systematic review. Toxin Reviews, 41(3), 995–1006. https://doi.org/10.1080/15569543.2021.1929323
Fikry, M., Alqahtani, N., Ali, S. A., Ghazzawy, H. S., Makki, H., Dinar, H., & Umar, M. (2026). Postharvest preservation and valorization of date palm. Cogent Food & Agriculture, 12(1), Article e2635137. https://doi.org/10.1080/23311932.2026.2635137
Focker, M., Liu, C., Wang, X., & van der Fels-Klerx, H. J. (2025). Artificial intelligence in mycotoxin management. Mycotoxin Research, 41(4), 529–540. https://doi.org/10.1007/s12550-025-00602-4
Gozzi, M., Blandino, M., Bruni, R., Capo, L., Righetti, L., & Dall’Asta, C. (2024). Mycotoxin occurrence in cereals. Mycotoxin Research, 40(1), 203–210. https://doi.org/10.1007/s12550-024-00521-w
Gruber-Dorninger, C., Aleschko, M., Höbartner-Gußl, A., Fruhauf, S., Thamhesl, M., Doupovec, B., & Pender, C. (2025). Enzyme technologies for mycotoxin mitigation in feed. Journal of Applied Poultry Research, 34(3), Article e100544. https://doi.org/10.1016/j.japr.2025.100544
Huang, J., Zhou, C., Huang, H., Yang, Z., & Liu, S. (2026). Cold plasma for food safety and mycotoxin decontamination. Molecules, 31(3), Article e517. https://doi.org/10.3390/molecules31030517
Islam, F., Saeed, F., Afzaal, M., Ahmad, A., Hussain, M., Khalid, M. A., & Khashroum, A. O. (2022). Green technologies for food safety enhancement. Food Science & Nutrition, 10(9), 2855–2867. https://doi.org/10.1002/fsn3.2915
Kalagatur, N. K., Nagaraj, A., Poda, S., & Salla, H. R. (2024). Toxicological investigation of Fusarium toxins. Indian Journal of Biochemistry and Biophysics, 61(12), 838–845.
Laika, J., Annunziata, L., Molina-Hernandez, J. B., De Flaviis, R., Campana, G., Ricci, A., & Lopez, C. C. (2024). Alternaria toxins reduction using plasma. Food Control, 164, Article e110563. https://doi.org/10.1016/j.foodcont.2024.110563
Lima da Silva, J., Lombardi, S., Castaldo, L., Morelli, E., Garda-Buffon, J., Izzo, L., & Ritieni, A. (2023). Multi-mycotoxin analysis in grains. Toxins, 15(9), Article e562. https://doi.org/10.3390/toxins15090562
Lopes, P., Sobral, M. M. C., Lopes, G. R., Martins, Z. E., Passos, C. P., Petronilho, S., & Ferreira, I. M. (2023). Mycotoxins in food by-products: A review. Toxins, 15(4), Article e249. https://doi.org/10.3390/toxins15040249
Maioto, R., Santos, S., Dias, A. A., Aires, C., Inês, A., Sedrine, N. B., & Sampaio, A. (2026). UV radiation applications in food industry. Applied Sciences, 16(4), Article e1877. https://doi.org/10.3390/app16041877
Molina-Hernandez, J. B., Grande-Tovar, C. D., Neri, L., Delgado-Ospina, J., Rinaldi, M., Cordero-Bueso, G. A., & Chaves-López, C. (2025). Non-thermal technologies for fungal contamination control. Frontiers in Microbiology, 16, Article e1543716. https://doi.org/10.3389/fmicb.2025.1543716
Monteiro, C. S., Pinto, E., López-Ruiz, R., Marín-Sáez, J., Frenich, A. G., Faria, M. A., & Cunha, S. C. (2025). Fungi contamination and mycotoxins in rice. Toxins, 17(9), Article e468. https://doi.org/10.3390/toxins17090468
Naseem, T., Altemimi, A. B., Ali, K., Zahid, N., Fatima, S., Naeem, M., & Aadil, R. M. (2026). Tomato juice preservation technologies. Future Foods, Article e100956. https://doi.org/10.1016/j.fufo.2026.100956
Nwabor, O. F., Onyeaka, H., Miri, T., Obileke, K., Anumudu, C., & Hart, A. (2022). Cold plasma technology for microbiological safety of foods. Food Engineering Reviews, 14(4), 535–554. https://doi.org/10.1007/s12393-022-09316-0
Obileke, K., Onyeaka, H., Miri, T., Nwabor, O. F., Hart, A., Al-Sharify, Z. T., & Anumudu, C. (2022). Advances in radio frequency, pulsed light, and cold plasma technologies for food safety. Journal of Food Process Engineering, 45(10), Article e14138. https://doi.org/10.1111/jfpe.14138
Oliveira, A. C. D. D., Ali, S., Corassin, C. H., Ullah, S., Pereira, K. N., Walsh, J. L., & Oliveira, C. A. F. D. (2025). Cold atmospheric plasma for decontamination of fungi and mycotoxins. Frontiers in Microbiology, 15, Article e1502915. https://doi.org/10.3389/fmicb.2024.1502915
Pandiselvam, R., Kothakota, A., & Rathnakumar, K. (Eds.). (2025). Ozone applications in the food industry: Trends and future prospects. CRC Press. https://doi.org/10.1201/9781003609827
Parray, J. A., Mir, M. Y., Shafi, N., & Haghi, A. K. (2025). Ozone applications in meat processing and seafood. In J. A. Parray, M. Y. Mir, N. Shafi, A. K. Haghi (Eds,), Ozone technology for food processing and preservation (pp. 55–76). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-81461-7_4
Pawale, A. V., Alaguthevar, R., Murugesan, B., Subburamu, K., Alagarsamy, S., & Rhim, J. W. (2025). Millet-based functional foods and non-thermal strategies. Journal of Food Process Engineering, 48(12), Article e70282. https://doi.org/10.1111/jfpe.70282
Pravallika, K., Pradhan, S., Prabha, A., & Chakraborty, S. (2025). Ultraviolet and pulsed light treatment of spices and herbs. Comprehensive Reviews in Food Science and Food Safety, 24(2), Article e70107. https://doi.org/10.1111/1541-4337.70107
Sitoe, E. D. P. E., Pacheco, F. C., & Chilala, F. D. (2025). Ozone technology for grain preservation and mycotoxin mitigation. Comprehensive Reviews in Food Science and Food Safety, 24(3), Article e70173. https://doi.org/10.1111/1541-4337.70173
Stuhldreier, F., Schmitt, L., Lenz, T., Hinxlage, I., Zimmermann, M., Wollnitzke, P., & Wesselborg, S. (2022). Viriditoxin induces apoptosis in leukemia and lymphoma. Cell Death & Disease, 13(11), Article 938. https://doi.org/10.1038/s41419-022-05356-w
Sujayasree, O. J., Pandiselvam, R., Kumar, P. C., Nayaka, V. K., Pooja, A., Chaitanya, A. K., & Ranjitha, K. (2025). Role of ozone in detoxification of mycotoxins. In R. Pandiselvam, A. Kothakota, & K. Rathnakumar (Eds.), Ozone applications in the food industry (pp. 57–94). Apple Academic Press. https://doi.org/10.1201/9781003609827-3
Tchonkouang, R. D., Lima, A. R., Quintino, A. C., Cristofoli, N. L., & Vieira, M. C. (2023). UV-C light for preservation of vegetable-based foods. Foods, 12(17), Article 3227. https://doi.org/10.3390/foods12173227
Teixeira, S. C., Batista, L. F., de Oliveira, A. A., Souza, M. I. P., Silvestre, S. I. L., Ferreira, D. C. M., & de Oliveira, T. V. (2026). Nanotechnology in food safety: Advanced detection approaches. In B. Prakash, & J. F. B. de São José (Eds.), Nanotechnology in food safety and sustainability (pp. 157–179). Springer Nature Switzerland. https://doi.org/10.1007/978-3-032-09287-8_6
Tiwari, S., & Dubey, N. K. (2025). Nanoformulated essential oils against fungal contamination. Indian Journal of Natural Products and Resources, 16(1), 13–28.
Tomas, M. K., & Jurčević Šangut, I. (2025). Mycotoxin contamination, detection, and mitigation. Toxins, 17(10), Article e515. https://doi.org/10.3390/toxins17100515
Wang, J., Tolosa, J., Wang, W., & Yang, X. (2025). Mycotoxins and fungal toxins: Current status and perspectives. Toxins, 17(4), Article e176. https://doi.org/10.3390/toxins17040176
Wang, Y., Liu, W., Li, L., Cao, W., Chen, J., Law, C. L., & Duan, X. (2026). Microbiological safety of dehydrated foods. Critical Reviews in Food Science and Nutrition, 1–17. https://doi.org/10.1080/10408398.2025.2611319
Wang, Y., Zhou, A., Yu, B., & Sun, X. (2024). Non-contact food decontamination technologies. Foods, 13(14), Article e2244. https://doi.org/10.3390/foods13142244
Yaya-González, A., Laika, J., & Peralta-Ruiz, Y. (2025). Emerging nonthermal technologies for food safety. Current Opinion in Chemical Engineering, 49, Article e101178. https://doi.org/10.1016/j.coche.2025.101178
Yousefi, M. H., Abbasi, E., Hadidi, M., Hashemi, S., Ghadimi, A. H., Yousefinejad, S., & Mousavi Khaneghah, A. (2023). Analysis of mycotoxins and contaminants in rice. Toxins, 15(2), Article e102. https://doi.org/10.3390/toxins15020102
Yousefi, M., Andishmand, H., Abedi-Firoozjah, R., Khorram, S., & Ostadrahimi, A. (2025). Detoxification of aflatoxin B1 using plasma. Journal of Food Quality and Hazards Control, 12(3), 230–239. https://doi.org/10.18502/jfqhc.12.3.19788
Zapaśnik, A., Bryła, M., Sokołowska, B., & Waśkiewicz, A. (2025). Pleurotus spp. in mycotoxin degradation: A review. Mycotoxin Research, 41(1), 1–13. https://doi.org/10.1007/s12550-024-00572-z
Zavala, A., Cavieres, O., Labbé, M., & Salazar, F. (2026). Ultraviolet technologies for yeast control in food industry. Foods, 15(6), Article e1102. https://doi.org/10.3390/foods15061102
