https://journals.smarcons.com/index.php/mls/issue/feed Medical and Life Sciences 2026-09-21T19:11:12+01:00 Editor MLS mls@smarcons.com Open Journal Systems <p>Medical and Life sciences (MLS) is a peer-reviewed, Open Access journal that publishes original research articles, Case studies, letter to editor, and review articles etc. covering a wide range of subjects in medicals and life sciences. <span lang="EN-US">All manuscripts are subject to peer review and are expected to meet standards of academic excellence. If approved by the editor, submissions will be considered by peer reviewers, whose identities will remain anonymous to the authors.</span></p> https://journals.smarcons.com/index.php/mls/article/view/475 Data-Driven Approaches to Healthcare Resource Optimization 2026-08-02T17:14:09+01:00 Waleed Arshad waleedarshad122@gmail.com Muneeb Arshad muneebarshad232@gmail.com Maheen Arshad maheenarshad222@gmail.com Muhammad Asjad Khan asjad.khan@vu.edu.pk Fizza Shahid fizzashahaid32@gmail.com Sara Aslam saraaslam232@gmail.com Arooba arooba232@gmail.com <p>Resource optimization in healthcare has emerged as a critical strategy to balance rising global healthcare demands with constrained financial, infrastructure, and human resources. This review synthesizes recent advances, challenges, and opportunities in optimizing healthcare delivery through data-driven allocation, scheduling, and workload management. Historical milestones reveal a trajectory from early applications of research in clinical logistics to the integration of explainable Artificial Intelligence (AI) and predictive platforms in modern systems. Foundational pillars of optimization, such as resource allocation, workload balance, and scheduling, are shown to directly impact patient wait times, staff burnout, and cost efficiency. The review highlights the transformative role of AI, Machine learning (ML), and operations research (OR) in predictive modeling, real-time decision support, and dynamic scheduling. Case studies demonstrate the success of AI-powered hospital bed forecasting, ML-driven surgical scheduling, and predictive staffing models in improving patient flow, reducing variability, and enhancing responsiveness during crises. Likewise, the integration of the Internet of Things (IoT), cloud, fog, and edge computing has enabled real-time monitoring and rapid decision-making in critical care. Spatial optimization models, including maximal coverage and P-median approaches, are further examined in their role in ensuring equitable healthcare access, particularly in underserved and rural regions. Despite these achievements, significant challenges persist. Data fragmentation, algorithmic bias, resistance to organizational change, and regulatory complexities hinder large-scale implementation. Solutions proposed include ontology–based interoperability frameworks, Blockchain-enabled data governance, fairness-aware algorithms, and structured change management models. Emerging trends highlight the increasing importance of equity-driven spatial optimization, hybrid AI-GIS approaches, and collaborative governance to reduce disparities and enhance resilience. This review concludes that resource optimization in healthcare is no longer an ethical option but a strategic imperative. By harnessing predictive analytics, advanced optimization algorithms, and equity-centered frameworks, healthcare systems can achieve efficiency, resilience, and fairness. However, realizing these benefits requires a multidisciplinary approach that integrates technological innovation, policy alignment, and stakeholder engagement. The future of healthcare resource management lies in scalable, explainable, and equitable solutions capable of adapting to dynamic global health challenges</p> 2026-08-01T00:00:00+01:00 Copyright (c) 2026 https://journals.smarcons.com/index.php/mls/article/view/496 Circular Economy of Mushroom Cultivation and Used Substrate Potential for Various Valuable Products 2026-09-21T01:27:25+01:00 Muhammad Awais Fareed awaisfareed069@gmail.com Mazeera Fatima mazeerafatima23@gmail.com Shahzaib Asghar shahzaibasghr22@gmail.com Zara Zahid zarazahid2332@gmail.com Muhammad Tayyab Mateen tayyabmateen232@gmail.com Abdul Basit Latif abdulbasit32@gmail.com Iram Bilqees IramBilqees232@gmail.com Sonum Bashir SonumBashir242@gmail.com <p>Mushroom is one of the fastest-growing and most dynamic industries within the world agricultural sector, as the mushroom industry is continuously being industrialized in Asia, Europe and North America, and as mushroom consumption keeps increasing as a source of high-quality and low-impact protein. In fact, this growth creates an ever increasing by-product which is spent mushroom substrate (SMS) the lignocellulosic material that remains after mushroom fruiting bodies are collected. When not re-used, SMS is a lost resource and an environmental burden, increasing GHG emissions, leachate pollution and disposal expenses. This review brings together current knowledge of the production trends and mushroom potential for global and regional production, mushroom properties and nutritional benefits in human nutrition as well as the mushroom valorisation process and possibilities. Its applications in the soil as compost and biofertiliser for enhancing soil structure and fertility, as a poultry and ruminant feed ingredient, as a feed ingredient for aquaculture species and farmed insects as a second generation feedstock for bio-organic production of bio-gas, bio-ethanol and bio-char and as a source of residual lignocellulolytic enzymes and recovered bioactive compounds for nutraceutical and pharmaceutical applications. In all these applications, the evidence is mounting for an integrated biorefinery strategy where several value streams are extracted from a single substrate before any waste product is returned to the soil, instead of SMS being considered as a single-use waste product. However, this potential needs to be realised on a wider scale, including the need to standardize the characterization of the substrate, increase investment in large-scale field and techno-economic studies and integrate better the mushroom farms with the surrounding agricultural, livestock and energy sectors. This review brings together recent developments in these areas and reconsiders the role of spent mushroom substrates as an agricultural waste problem rather than a solution. This review has consolidated the latest developments in these areas and rethought the role of spent mushroom substrates as a contribution to a circular bioeconomy rather than the problem of agricultural waste.</p> 2026-09-20T00:00:00+01:00 Copyright (c) 2026 https://journals.smarcons.com/index.php/mls/article/view/497 Eating Smart Intended for Diabetes Management: An Updated Review 2026-09-21T06:20:35+01:00 Samina Kauser samina.kauser@uos.edu.pk Mehak Fatima mehakfatima232@gmail.com Aqib Ishaq aqibishaq019@gmail.com Mudassra Asghar modassarasghar21@gmail.com Sawera Munir saweramunir22@gmail.com Amber Khalil amberkhalil334@gmail.com Muhammad Abubakar abunbakar232@gmail.com Muhammad Soban Mumtaz MuhammadSobanMumtaz434@gmail.com Zoobia Nadeem zobianadeem23@gmail.com <p>Globally, 425 million people are affected by diabetes, making India the country with the second-highest number of T2DM sufferers. The current increasing trend of the epidemic is a consequence of an unhealthy and sedentary lifestyle, particularly in lower- and middle-income countries. Diabetes Nutrition Therapy (DNT) and Women's Lifestyle Interventions (WLIs) are significant aspects of diabetes. Diabetic medical nutrition therapy (MNT) and diabetes medications should be evaluated and reviewed at medical visits. The American Diabetes Association and the Academy of Nutrition and Dietetics are revising the nutrition therapy recommendations for adults with diabetes; it's estimated that the global population with the disease will reach 693 million by 2045.Lifestyle modifications include Diabetes Nutrition Therapy (DNT) and consist of physical activity, diet (small weight loss), and an important component of diabetes care for the management of diabetes complications. India has been the second largest population of type 2 diabetes mellitus (T2DM) in the world with more than 72 million people in 2017.Diabetes Nutrition Therapy (DNT) is essential for better metabolic and glycemic control, and is a key component in the management of T2DM complications. There are multidisciplinary collaborative groups such as Indian Council of Medical Research, Research Society for the Study of Diabetes in India that fosters comprehensive lifestyle changes, which include MNT. The Academy of Nutrition and Dietetics and the American Diabetes Association are revising recommendations for nutrition therapy for adults with diabetes, particularly in India which has the second-largest number of T2DM patients. MNT is crucial for diabetes management and management of complications and a Mediterranean diet can reduce the risk of cardiovascular disease (CVD) in at-risk individuals.</p> 2026-09-20T00:00:00+01:00 Copyright (c) 2026 https://journals.smarcons.com/index.php/mls/article/view/498 A Polyherbal Blend for Cardiovascular Wellness: Exploring the Synergistic Effects of Arjuna, Cinnamon, Cardamom, and Green Tea 2026-09-21T19:11:12+01:00 Kanzul Emaan Aslam emann45265@gmail.com Shaheer Ul Hassan shaheer23@gmail.com Ayesha Zainab ayeshazainab23@gmail.com Fizza Shahid fizzashahaid32@gmail.com Momina Batool MominaBatool3242@gmail.com Kamran Tahir kami232@gmail.com <p>Cardiovascular disease continues to be a major worldwide health issue. Arjuna (Terminalia arjuna) bark, well known for its cardioprotective qualities, is a promising remedy in traditional Ayurvedic medicine. to find out how effectively a polyherbal tea blend that includes green tea, cardamom, cinnamon, and Arjuna bark can support cardiovascular health. One hundred people with moderate hypertension participated in a randomised, double-blind, placebo-controlled study. For 12 weeks, participants received the Arjuna tea blend or a placebo twice a day. The Arjuna tea group showed a significant decrease in systolic blood pressure (-8.5 mmHg) when compared to the placebo group. They also showed improvements in lipid profiles (increased HDL, decreased LDL, and triglycerides), improved endothelial function (increased nitric oxide production), and decreased inflammatory markers (C-reactive protein and IL-6). The synergistic effects of the herbs in the Arjuna tea blend likely drive its strong cardiovascular benefits. Arjuna's cardioprotective effects are complemented by the insulin-sensitizing qualities of cinnamon, the antioxidant and anti-inflammatory activities of cardamom, and the catechin-rich profile of green tea. For preserving cardiovascular health, this polyherbal tea provides a convenient, safe, and efficient supplemental treatment.</p> 2026-09-20T00:00:00+01:00 Copyright (c) 2026