The Exploring the supremacy of Azadirachta Indica (neem) as a Medicinal Agent
Keywords:
Antioxidant, anticancer, azadirachtin, querectin, signaling pathway, Methanolic extract, phenolic compound, antifungal.Abstract
The historical use of herbs as medicine is confirmed in Islamic perception. Among the extensively used medicinal plants, neem is the essential one. Neem, a member of the family Meliaceae is being widely used in disease management now a day. It is well thought to be a safe and eco-friendly plant of this era. signalling parts of this plant, like leaves, stem roots, and flowers, hold a diversity of biologically active compounds. These compounds are being extracted. Among the chief compounds is azadirachtin. These compounds exhibit antimicrobial, antioxidant, anti-inflammatory, anti-fertility, hepatoprotective, and neuroprotective activities. Moreover, its constituents comprise a therapeutic inference in the induction of cell signaling pathways in cancer management. Recent studies have also exposed its neuroprotective affinity against a wide range of neurotoxins in brain tissues. This review summaries the major biochemical constituents of neem and their pharmacological miracles in the medical community.
